|
KMID : 1142020230580010013
|
|
Blood Research
2023 Volume.58 No. 1 p.13 ~ p.19
|
|
|
The impact of COVID-19 on acute myeloid leukemia patients undergoing allogeneic stem cell transplantation: a concise review
|
|
Reham Osama Mansour
Shaimaa El-Ashwah
May Denewer
|
|
|
Abstract
|
|
|
|
This study aimed to delineate the possible impact of COVID-19 on acute myeloid leukemia (AML) patients in terms of diagnosis, chemotherapy, bone marrow transplant, and vaccination response. Allogeneic stem cell transplantation is markedly affected by the COVID-19 pandemic, as both donors and recipients must be healthy for transplantation to be feasible and successful. Delays in the identification of well-matched donors have been predicted, and represent a special challenge. Therefore, future donors should be tested for COVID-19. The outcome of delayed transplantation is vague and masked by variations in stem cell source along with disease subtype. However, if transplant delay results in recurrence of minimal residual disease, a negative impact on survival is anticipated.
|
|
|
KEYWORD
|
|
|
Allogeneic-stem cell transplantation, Acute myeloid leukemia, COVID-19, SARS-CoV-2
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|